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In 1979, 6-year-old Etan Patz was murdered. Pedro Hernandez, convicted in 1985, faces a new trial after a 2025 federal appeals court ruling. The Manhattan District Attorney announced plans to retry him in November 2025.

In 2005, a violent brawl at a Melbourne party resulted in a 22-year-old man's death. An 18-year-old boxer, Khalid Baker, was convicted of murder despite claiming innocence and presenting evidence. Another man later asserted responsibility, but the teenager was acquitted. After serving a 13-year sentence, Baker continues fighting for his innocence.

A man accused of killing his model girlfriend and another woman evaded FBI capture for years before being jailed in Mexico. Oswaldo Perez-Sanchez faces charges linked to the deaths, with authorities citing his prolonged evasion and current detention.

Harshita Brella's body was discovered in a car trunk 100 miles from her London home last fall. Investigators suspect her husband, Pankaj Lamba, murdered her and fled the UK. Lamba remains at large, but his parents have been charged in connection with the crime.

A severed arm with tattoos found in Illinois’ Lake Mattoon led to the identification of 38-year-old Dalewayne Turner. Investigators recovered additional body parts from a freezer, resulting in arrests of family members on charges of concealing homicide and dismemberment. Authorities are now examining how Turner died and how his remains were dispersed between his home and the lake.

On December 29, 2018, a bar scuffle resulted in Anthony Bankston's death. Detectives struggled to identify the killer, as witnesses recalled a man shooting him but could not describe his face, complicating the investigation. The crime scene's chaotic nature and conflicting accounts hindered progress in locating the perpetrator.

Brandon Lawson disappeared in 2013 after his car broke down, leaving him stranded and calling 911 as he claimed to be chased through the woods. The case remains unsolved despite investigations finding no evidence in the area.

Jeroen Coombs faces murder charges for 3-year-old Paisley Brown's death. Bodycam footage from 2019 shows him attacking a woman holding an infant, though no conviction followed. The case resurfaces as a potential death penalty decision approaches, prompting renewed scrutiny of his past actions.

The Manchester Arena bombing in 2017 killed 22 people, including children, when Salman Abedi detonated a bomb at an Ariana Grande concert. His brother, Hashem Abedi, was later prosecuted for his role. Investigations highlighted intelligence failures, community radicalization linked to ISIS, and led to Martyn's Law to enhance counter-terrorism measures.

Manchester detectives investigated a river murder case after swimmers found dismembered remains. The investigation uncovered evidence linking suspects to the crime, leading to the arrest and conviction of Phil Jeans for the murder of Jennifer Lewis. Key clues and witness testimonies were critical in solving the case.

The series profiles members of the Quality Street Gang, including Paul Massey and others, through interviews revealing their criminal activities and underworld connections.

The episode profiles three British serial killers linked to Manchester's 1960s child abductions, using survivor interviews, dramatic reconstructions, and archive footage to detail their crimes and the survivors' pivotal role in convictions.