H.H. Holmes was an American serial killer active in the late 19th century, often associated with a specially constructed building in Chicago known as the “Murder Castle.” He used the structure to facilitate a series of murders, many of which remain difficult to fully document. Holmes was eventually arrested and confessed to multiple killings, though the exact number of victims remains debated. He was executed in 1896, and his case remains one of the earliest and most infamous examples of serial murder in the United States.
Vincent Ambrosio is an American teenager who was convicted of murdering a young girl in Maryland in 2018. The case drew attention due to his age and the disturbing nature of the crime. Investigations revealed troubling behavior and warning signs prior to the killing, leading to discussions about juvenile offenders and early intervention. His conviction resulted in a lengthy prison sentence, reflecting the severity of the crime.
Richard Cottingham, known as the “Torso Killer,” is an American serial killer responsible for a series of murders in the 1970s, primarily targeting women in New York and New Jersey. His crimes were marked by extreme violence and mutilation. After his arrest, Cottingham was convicted of multiple murders and later confessed to additional killings. His case remains one of the most disturbing in U.S. criminal history, with ongoing investigations continuing to uncover further victims.

Michael Swango became one of the most notorious medical serial killers in American history after being linked to a series of poisonings involving patients, coworkers, and acquaintances over several decades. A licensed physician and former paramedic, Swango exploited positions within hospitals and medical institutions to gain access to vulnerable victims while maintaining the outward image of a highly educated healthcare professional. The case generated international attention because Swango continued obtaining medical employment despite repeated suspicions, disciplinary actions, and criminal convictions. Investigators later connected him to deaths and poisonings across the United States and Africa, leading many experts to believe the true number of victims may never be fully known. His ability to repeatedly evade detection turned the case into one of the most disturbing examples of institutional failure and medical predation in modern criminal history.
Rodney Alcala was an American serial killer and sex offender who murdered multiple women and girls between the 1960s and 1970s. He gained notoriety for appearing on the television show "The Dating Game" during his killing spree. Alcala was eventually convicted of several murders and linked to many more through DNA evidence. He spent decades on death row before dying in prison in 2021. His case remains infamous due to the sheer number of victims and his ability to evade capture for years.
David Carpenter, known as the "Trailside Killer," is an American serial killer responsible for a series of murders in California during the late 1970s and early 1980s. He targeted victims in remote park areas, often attacking hikers along trails. Carpenter was eventually arrested and convicted of multiple murders, receiving a death sentence. His case remains notable for the fear it instilled among outdoor communities and the extensive manhunt that led to his capture.
Charles Albright, known as the "Eyeball Killer," was an American murderer convicted of killing sex workers in Texas in the early 1990s. His nickname came from the disturbing mutilation of his victims. Albright was convicted of one murder, though he is suspected in several others. He spent the remainder of his life in prison until his death in 2020. His case remains one of the more unusual and disturbing in U.S. criminal history.
Tony Costa was an American serial killer known for the "Cape Cod Vampire" murders in the 1960s. He killed multiple young women, dismembering their bodies and burying them in wooded areas near Provincetown, Massachusetts. Costa was eventually arrested and convicted, receiving a life sentence. He died by suicide in prison in 1974. His case remains one of the most notorious serial murder cases in New England history.

Jeffrey Dahmer is one of the most disturbing figures in American criminal history, often dubbed the “Milwaukee Cannibal.” Between 1978 and 1991, he carried out a series of brutal murders involving necrophilia, cannibalism, and body preservation. His crimes shocked the world not only for their severity, but for how long he evaded capture.
Ed Gein was an American murderer and body snatcher whose crimes in Wisconsin during the 1950s shocked the nation. He exhumed corpses and used body parts to create household items, as well as committing at least two murders. Gein was arrested in 1957 and later found legally insane, spending the rest of his life in a psychiatric institution. His case inspired numerous fictional characters and remains one of the most disturbing in U.S. criminal history.
Roy DeMeo was an American mobster associated with the Gambino crime family, known for leading a crew responsible for numerous murders during the 1970s and early 1980s. His group became infamous for their efficiency in carrying out contract killings. DeMeo was eventually murdered, likely by members of organized crime due to fears he would cooperate with authorities. His case remains a significant example of organized crime violence in the United States.
Carmine Galante was an American mob boss within the Bonanno crime family, heavily involved in organized crime activities including drug trafficking and contract killings. He played a major role in expanding heroin distribution networks in the United States. Galante was assassinated in 1979 in a mob-related hit, marking a turning point in internal Mafia power struggles. His life and death are closely tied to the violent dynamics of organized crime during that era.
Sam Giancana was an American mob boss who led the Chicago Outfit and became one of the most powerful figures in organized crime during the mid-20th century. He was involved in numerous criminal enterprises, including illegal gambling and contract killings. Giancana was assassinated in 1975 shortly before he was scheduled to testify before a Senate committee. His death remains surrounded by speculation and is often linked to his connections with organized crime and political figures.
Erin Caffey is an American woman convicted for orchestrating the murder of her mother and two younger brothers in Texas in 2008. At just 16 years old, she persuaded her boyfriend and accomplices to carry out the killings after her parents disapproved of the relationship. The case shocked the public due to her age and the calculated nature of the crime. Caffey was later sentenced to life imprisonment, and her case remains a disturbing example of manipulation and family-directed violence.
Bernard Giles is an American serial killer responsible for the murders of multiple young women in the 1970s. His crimes involved targeting vulnerable victims and using deception to gain their trust. Giles was eventually arrested and convicted, receiving a lengthy prison sentence. His case remains one of the lesser-known serial murder cases from that era but is notable for its brutality and pattern of offenses.
Lorenzo Gilyard is an American serial killer known as the "Kansas City Strangler," responsible for the murders of multiple women in Missouri during the late 1970s. His crimes were characterized by strangulation and targeting vulnerable victims. Gilyard was eventually arrested and convicted, receiving multiple life sentences. His case remained unsolved for years before advancements in forensic techniques helped link him to additional murders.
Mark Riebe is an American man convicted of the murder of a young woman in Florida in 1998, a case that remained unsolved for years before being reopened with new evidence. He was later linked to the killing through advances in forensic investigation. Riebe was convicted and sentenced to life imprisonment. His case highlights how cold cases can eventually be solved through persistence and improvements in investigative techniques.
David Battaglia was an American man convicted of murdering his two young daughters in Texas in 2001. The crime occurred during a custody dispute and was carried out while he was on the phone with their mother. Battaglia was sentenced to death and executed in 2018. The case drew significant attention due to the circumstances of the killings and the legal debates surrounding his mental competency.
Gary Green was an American man convicted of the murders of his estranged wife and her young daughter in Texas. The killings were carried out in a violent domestic incident that shocked the community. Green was sentenced to death and later executed in 2023. His case is one of several high-profile executions in Texas involving domestic violence-related murders.
Stephen Corey Bryant was an American serial killer responsible for multiple murders in South Carolina. His crimes involved extreme violence and targeted multiple victims over time. Bryant was convicted and sentenced to death, eventually being executed by firing squad. His case drew attention due to the method of execution and the severity of his crimes.